Alcohol makes you feel drunk primarily due to its effects on the central nervous system. When you consume alcoholic beverages, the ethanol (the type of alcohol found in alcoholic drinks) is absorbed into your bloodstream through the stomach and small intestine. From there, it quickly reaches your brain.

Here's how alcohol affects your brain and body, leading to the sensation of being drunk:

1. Impact on Neurotransmitters: Alcohol affects neurotransmitters in the brain, particularly gamma-aminobutyric acid (GABA) and glutamate. GABA is an inhibitory neurotransmitter that slows down brain activity, leading to feelings of relaxation and calmness. Glutamate, on the other hand, is an excitatory neurotransmitter that is suppressed by alcohol, further contributing to the depressant effects.

2. Disruption of Brain Function: Alcohol disrupts the normal functioning of various regions of the brain, including those responsible for judgment, inhibition, coordination, and decision-making. This disruption leads to impaired cognitive and motor functions, affecting your ability to think clearly, make rational decisions, and coordinate movements.

3. Changes in Blood Flow: Alcohol can cause changes in blood flow to the brain, altering the brain's oxygen supply and contributing to feelings of dizziness and disorientation.

4. Dehydration: Alcohol is a diuretic, meaning it increases urine production and can lead to dehydration. Dehydration can worsen the symptoms of intoxication, such as headaches, dizziness, and fatigue.

5. Toxic Effects: While moderate alcohol consumption may not pose significant health risks for most people, excessive drinking can lead to alcohol poisoning. Alcohol poisoning occurs when there is a toxic buildup of alcohol in the bloodstream, leading to severe symptoms such as vomiting, unconsciousness, slowed or irregular breathing, and even death in extreme cases.

6. Individual Factors: The effects of alcohol can vary depending on factors such as body weight, metabolism, tolerance, and the presence of food in the stomach. Additionally, genetic factors can influence how a person responds to alcohol and their susceptibility to becoming intoxicated.

Overall, the combination of alcohol's effects on neurotransmitters, brain function, and bodily processes leads to the sensation of being drunk. It's important to consume alcohol responsibly and be aware of its potential effects on your body and behavior.